
孔二艳教授
新乡医学院特聘教授,留学德国获得神经生物学博士学位并在美国NIH从事博士后研究。课题组已承担10多项国科基金并在PNAS和Science Signaling等知名期刊发表科研论文30余篇。兼职中国病理生理学会和中国科协科创。
主要研究方向:蛋白质棕榈酰化修饰的分子和生理功能
Liu, H., Yan, P., Wu, C., Rao, M., Zhu, J., Lv, L., Li, W., Liang, Y., Qi, S., Lu, K., and Kong, E. # (2023) Palmitoylated Sept8-204 modulates learning and anxiety by regulating filopodia arborization and actin dynamics. Science Signaling 16, eadi8645.(IF=6.7)
Tang, D., Zheng, K., Zhu, J., Jin, X., Bao, H., Jiang, L., Li, H., Wang, Y., Lu, Y., Liu, J., Liu, H., Tang, C., Feng, S., Dong, X., Xu, L., Yin, Y., Dang, S., Wei, X., Ren, H., Dong, B., Dai, L., Cheng, W., Wan, M., Li, Z., Chen, J., Li, H., Kong, E.#, Wang, K. #, Lu, K. #, and Qi, S. # (2023) ALS-linked C9orf72-SMCR8 complex is a negative regulator of primary ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America 120, e2220496120.(IF=11.1)
Zhou B, Wang Y, Zhang L, Shi X, Kong H, Zhang M, Liu Y, Shao X, Liu Z, Song H, Li W, Gao X, Chang Y, Dou C, Guo W, Zhang S, Kang X, Gao J, Liang Y, Zheng J, Kong E. # (2022). The palmitoylation of AEG-1 dynamically modulates the progression of hepatocellular carcinoma. Theranostics. 12(16):6898-6914.(IF=12.4)
Yan, P., H. Liu, T. Zhou, P. Sun, Y. Wang, X. Wang, L. Zhang, T. Wang, J. Dong, J. Zhu, L. Lv, W. Li, S. Qi, Y. Liang and E. Kong# (2022). "Crosstalk of Synapsin1 palmitoylation and phosphorylation controls the dynamicity of synaptic vesicles in neurons." Cell Death & Disease 13(9): 786.(IF=9.0)
Yuan, W., L. Lu, M. Rao, Y. Huang, C. E. Liu, S. Liu, Y. Zhao, H. Liu, J. Zhu, T. Chao, C. Wu, J. Ren, L. Lv, W. Li, S. Qi, Y. Liang, S. Yue, J. Gao, Z. Zhang and E. Kong# (2021). "GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice." Proceedings of the National Academy of Sciences of the United States of America 118(13).(IF=11.1)
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